Unsaturated oxyalkylene esters and uses thereof

A - Human Necessities – 01 – N

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A01N 37/10 (2006.01) C07C 69/618 (2006.01) C07C 69/65 (2006.01) C07C 69/734 (2006.01) C07C 69/76 (2006.01)

Patent

CA 2283306

This invention relates to compositions for and methods of treating, preventing or ameliorating cancer and other proliferative diseases as well as methods of inducing wound healing, treating cutaneous ulcers, treating gastrointestinal disorders, treating blood disorders such as anemias, immunomodulation, enhancing recombinant gene expression, treating insulin-dependent patients, treating cystic fibrosis patients, inhibiting telomerase activity, treating virus-associated tumors, especially EBV-associated tumors, modulating gene expression and particularly augmenting expression of a tumor suppressor gene and inducing tolerance to an antigen. The methods of the invention use unsaturated oxyalkylene esters.

L'invention concerne des compositions et des procédés de traitement, de prévention et de lutte contre le cancer et d'autres maladies prolifératives, ainsi que des procédés qui favorisent la cicatrisation, traitent les ulcérations cutanées, les troubles gastro-intestinaux, et les dysfonctionnements sanguins tels que l'anémie. Ces procédés favorisent également l'immunomodulation et l'expression génique recombinée, traitent les patients insulinodépendants et les patients souffrant de mucoviscidose, inhibent l'activité télomérase, traitent les tumeurs virales, notamment les tumeurs liées au virus Epstein-Barr, modulent l'expression génique, et en particulier augmentent l'expression d'un gène suppresseur de tumeur et encouragent la tolérance à un antigène. Les procédés de cette invention utilisent des esters oxyalkylène insaturés.

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