Unsolvated benzodiazepine compositions and methods

A - Human Necessities – 61 – K

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A61K 31/5513 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) C07D 243/24 (2006.01)

Patent

CA 2611031

The present invention relates to systems and methods for generating new forms of benzodiazepine and benzodiazepine related compounds as well as new compounds and formulations generated by such methods. In particular, the present invention provides high throughput systems and methods for generating and identifying new crystalline benzodiazepine and benzodiazepine related polymorphs and new unsolvated, solvated, and other forms of the compounds that find use as improved drugs and drag formations.

La présente invention concerne des systèmes et des méthodes permettant la création de nouvelles formes de benzodiazépine et de composés dérivés de benzodiazépine, ainsi que les nouveaux composés et les nouvelles formules créés par le biais de telles méthodes. En particulier, la présente invention concerne des systèmes et des méthodes à haut débit pour la création et l'identification de nouvelles formes cristallines de benzodiazépine et de nouvelles formes polymorphiques cristallines dérivées de benzodiazépine ainsi que de nouvelles formes non solvatées, solvatées, etc. pouvant être employées en tant que médicaments et formules de médicaments améliorés.

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