Unstructured recombinant polymers and uses thereof

Details Unstructured recombinant polymers and uses thereof Unstructured recombinant polymers and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/00 (2006.01) A61K 47/48 (2006.01) C07K 14/00 (2006.01) C12N 15/00 (2006.01) C12N 15/11 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) C40B 40/08 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2644712

The present invention provides unstructured recombinant polymers (URPs) andproteins containing one or more of the URPs. The present invention also provides microproteins, toxins and other related proteinaceous entities, as well as genetic packages displaying these entities. The present invention also provides recombinant polypeptides including vectors encoding the subject proteinaceous entities, as well as host cells comprising the vectors. The subject compositions have a variety of utilities including a range of pharmaceutical applications.

Cette invention concerne des polymères recombinés non structurés (URP) et des protéines contenant un ou plusieurs de ces polymères recombinés non structurés. Cette invention concerne également des microprotéines, des toxines et d'autres entités protéiques associées, ainsi que des matériels génétiques contenant ces entités. La présente invention concerne également des polypeptides recombinés comprenant des vecteurs codant pour les entités protéiques susmentionnées, ainsi que des cellules hôtes comprenant les vecteurs. Les compositions décrites dans cette invention ont une large gamme d'utilisations y compris un éventail d'applications pharmaceutiques.

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