Untriakontapeptide with opiate activity

C - Chemistry – Metallurgy – 07 – K

Patent

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530/7.44

C07K 14/675 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1092602

ABSTRACT Hentriakontapeptides of the sequence Image I wherein R1 is Ile or Val; R2 is His or Tyr and R3 is Gln or Glu, with opiate agonist activity and process for the preparation thereof by a) isolating such a compound from natural sources using procedures well known in the art or b) synthesizing such a compound using conventional solid phase peptide synthesis.

274024

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