Upregulation of rack-1 in melanoma and its use as a marker

Details Upregulation of rack-1 in melanoma and its use as a marker Upregulation of rack-1 in melanoma and its use as a marker

G - Physics

01

N

G01N 33/574 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2695060

The present invention concerns a method for diagnosing a melanoma in a mammal comprising the detection of the overexpression of RACK-1 protein in a melanocyte cell of said mammal, and the deduction of the presence of a melanoma from the overexpression of RACK-1 protein. The invention is also directed to a method for determining the tumoral status of a melanocyte cell of a mammal, comprising the detection of overexpression of RACK-1 protein in the melanocyte cell, and the deduction of the tumoral state of said cell from the overexpression of RACK-1 protein.

La présente invention concerne un procédé de diagnostic d'un mélanome chez le mammifère. Le procédé consiste à détecter la surexpression de la protéine RACK-1 dans une cellule mélanocyte du mammifère et à déduire la présence d'un mélanome à partir de la surexpression de la protéine RACK-1. L'invention concerne également un procédé pour déterminer l'état tumoral d'une cellule mélanocyte d'un mammifère. Le procédé consiste à détecter la surexpression de la protéine RACK-1 dans la cellule mélanocyte et à déduire l'état tumoral de la cellule à partir de la surexpression de la protéine RACK-1.

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