Ura5 gene and methods for stable genetic integration in yeast

Details Ura5 gene and methods for stable genetic integration in yeast Ura5 gene and methods for stable genetic integration in yeast

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/52 (2006.01) C12N 15/54 (2006.01) C12N 15/64 (2006.01) C12N 15/81 (2006.01) C12N 15/90 (2006.01) C12P 21/00 (2006.01)

Patent

CA 2525954

A novel gene encoding P. pastoris orotate-phosphoribosyl transferase (URA5) is disclosed. Methods for producing and selecting yeast strains capable of stable genetic integration of heterologous sequences into the host genome are also provided.

L'invention concerne un nouveau gène codant pour l'orotate-phosphoribosyl transférase (URA5) deP. pastoris. L'invention concerne également des procédés permettant de produire et de sélectionner des souches de levures permettant une intégration génétique stable de séquences hétérologues dans le génome hôte.

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