Urea and amide derivatives and their use in the control of...

C - Chemistry – Metallurgy – 07 – C

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C07C 275/34 (2006.01) A61K 31/155 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/17 (2006.01) A61K 31/195 (2006.01) A61K 31/24 (2006.01) A61K 31/245 (2006.01) A61K 31/275 (2006.01) A61K 31/44 (2006.01) C07C 233/29 (2006.01) C07C 235/38 (2006.01) C07C 275/30 (2006.01) C07C 275/32 (2006.01) C07C 275/38 (2006.01) C07C 275/40 (2006.01) C07C 275/42 (2006.01) C07C 279/18 (2006.01) C07C 279/28 (2006.01) C07C 335/18 (2006.01) C07D 213/63 (2006.01) C07D 213/75 (2006.01)

Patent

CA 2160128

A compound having formula (I) or a pharmaceutically acceptable salt thereof, wherein X and Z each independently are NH or CH2, at least one of X and Z being NH; Y is O, S, NCN, or NH; B, D, E and F each independently are C or N, at least three of B, D, E, and F being C; and R1, R2, R3, R4, R11, R12 have the meanings set forth in the specification, pharmaceutical compositions comprising the same, and a method of treating therewith. The compounds are useful as potassium channel openers.

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