Urea compounds and methods of uses

Details Urea compounds and methods of uses Urea compounds and methods of uses

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) C07D 213/40 (2006.01) C07D 213/75 (2006.01) C07D 417/04 (2006.01) C07D 417/12 (2006.01) C07D 453/06 (2006.01) C07D 471/04 (2006.01) C07D 491/10 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2418273

Selected novel urea compounds are effective for prophylaxis and treatment of diseases, such as cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving stoke, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

L'invention porte sur de nouveaux composés d'urée sélectionnés qui sont efficaces dans la prophylaxie et le traitement de maladies telles que la prolifération cellulaire et les maladies induites par l'apoptose. L'invention porte également sur de nouveaux composés, des analogues, des promédicaments et sur leurs sels acceptables d'un point de vue pharmaceutique, sur des compositions pharmaceutiques et sur des procédés prophylactiques et thérapeutiques utilisés pour traiter des pathologies ou états tels que des accidents vasculaires cérébraux, le cancer et analogue. Cette invention porte en outre sur des procédés de fabrication de ces composés, ainsi que sur des intermédiaires utilisés dans ces procédés.

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