C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/40 (2006.01) A61K 31/44 (2006.01) A61K 31/4709 (2006.01) A61P 25/28 (2006.01) C07D 213/61 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2722606
The present invention provides compounds Formula (I) that are gamma secretase modulators and are therefore useful for the treatment of diseases treatable by modulation of gamma secretase such as Alzheimer's disease. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
La présente invention concerne des composés de formule (I) qui sont des modulateurs de la gamma-sécrétase et sont par conséquent utiles pour le traitement de maladies susceptibles d'être traitées par la modulation de la gamma-sécrétase, comme la maladie d'Alzheimer. Elle concerne également des compositions pharmaceutiques contenant ces composés et des procédés pour préparer ces composés.
Biswas Kaustav
Chen Jian J.
Falsey James Richard
Gore Vijay Keshav
Liu Qingyian
Amgen Inc.
Gowling Lafleur Henderson Llp
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