Urea derivatives, a process for their preparation and...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/42 (2006.01) C07C 275/24 (2006.01) C07C 323/44 (2006.01) C07D 207/16 (2006.01) C07D 207/22 (2006.01) C07D 209/20 (2006.01) C07D 209/52 (2006.01) C07D 211/60 (2006.01) C07D 213/55 (2006.01) C07D 217/26 (2006.01) C07D 223/06 (2006.01) C07D 231/12 (2006.01) C07D 233/54 (2006.01) C07D 277/06 (2006.01) C07D 333/24 (2006.01) C07D 333/60 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 1307000

- 1 - HOE 81/F 228 Abstract of the disclosure: Compounds of the formula I I Image in which n denotes 0 - 3, R1 and R1' are the same or different and denote hydro- gen, alkyl or alkenyl, phenyl or benzyl, each substituted as desired; R2 denotes hydrogen, alkyl or alkenyl; R3 denotes hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl or aminoalkyl, alkanoylaminoalkyl, guanidinoalkyl, imidazolylalkyl,indolylalkyl, mercaptoalkyl or alkyl- thioalkyl, phenylalkyl, hydroxyphenylalkyl, phenoxyalkyl or phenylthioalkyl, or R2 and R3, together with the C and N atoms carrying them, denote a saturated or unsat- urated 4- to 8-membered monocyclic or 8- to 10-membered bicyclic isocycle or heterocycle, optionally monosub- stituted or disubstituted by hydroxyl, alkoxy having 1 to 3 C atoms or alkyl, R4 denotes hydrogen, alkyl, alkenyl, alkadienyl, alkinyl, alkeninyl or alkadiinyl, cycloalkyl, phenyl, benzyl, phenethyl or phenylpropyl, each of which can be - 2 - optionally monosubstituted or disubstituted; R5 denotes hydrogen or alkyl, hydroxyl or alkoxy and R6 denotes hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl, optionally monosubstituted or disubstituted phenyl or naphthyl, their salts, a process for their preparation and their use as medicaments.

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