Urea derivatives and their use as acat inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 275/28 (2006.01) A61K 31/17 (2006.01) A61K 31/33 (2006.01) C07C 275/32 (2006.01) C07C 275/34 (2006.01) C07C 323/44 (2006.01) C07D 207/14 (2006.01) C07D 209/08 (2006.01) C07D 209/16 (2006.01) C07D 211/16 (2006.01) C07D 211/22 (2006.01) C07D 211/42 (2006.01) C07D 211/48 (2006.01) C07D 211/56 (2006.01) C07D 211/58 (2006.01) C07D 211/60 (2006.01) C07D 213/40 (2006.01) C07D 213/56 (2006.01) C07D 213/75 (2006.01) C07D 213/82 (2006.01) C07D 215/08 (2006.01) C07D 217/06 (2006.01) C07D 265/30 (2006.01) C07D 295

Patent

CA 2123728

ABSTRACT Urea derivatives of formula (I) Image (I) wherein the valuable groups are as defined in the specification, which possess both an ACAT inhibitory activity and an antioxidative activity. Those derivatives are useful in the prophylaxis and treatment of hypercholesterolemia and atherosclerosis.

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