Urea derivatives and their use as acat inhibitors

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 275/40 (2006.01) A61K 31/17 (2006.01) A61K 31/33 (2006.01) C07C 275/34 (2006.01) C07C 275/42 (2006.01) C07D 207/14 (2006.01) C07D 211/58 (2006.01) C07D 213/56 (2006.01) C07D 213/75 (2006.01) C07D 231/04 (2006.01) C07D 237/20 (2006.01) C07D 295/215 (2006.01) C07D 317/66 (2006.01) C07D 471/08 (2006.01)

Patent

CA 2133394

Urea derivatives of formula (1) Image (1) wherein the valuable groups are as defined in the specification, which possess both an ACAT inhibitory activity and an antioxidative activity. Those derivatives are useful in the prophylaxis and treatment of hypercholesterolemia and atherosclerosis.

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