Urea derivatives as anti-inflammatory agents

Details Urea derivatives as anti-inflammatory agents Urea derivatives as anti-inflammatory agents

C - Chemistry, Metallurgy

07

D

C07D 213/68 (2006.01) A61K 31/44 (2006.01) A61K 31/5377 (2006.01) A61P 29/00 (2006.01) C07D 213/69 (2006.01) C07D 213/74 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2389360

Disclosed are novel aromatic compounds of formula (I) wherein G, X, Ar, L and Q are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases. Also disclosed are processes of making such compounds. The compounds (I) inhibit cytokine production.

L'invention concerne des composés aromatiques représentés par la formule (I) dans laquelle G, X, Ar, L et Q sont définis. Ces composés s'avèrent utiles dans des compositions pharmaceutiques destinées au traitement de maladies ou d'affections pathologiques associées à une inflammation telles que les maladies inflammatoires chroniques. L'invention se rapporte également à des procédés de production de tels composés. Ces composés (I) inhibent la production de cytokine.

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