Urea derivatives as integrin alpha 4 antagonists

Details Urea derivatives as integrin alpha 4 antagonists Urea derivatives as integrin alpha 4 antagonists

C - Chemistry, Metallurgy

07

D

C07D 275/00 (2006.01) C07C 275/28 (2006.01) C07C 275/40 (2006.01) C07C 275/42 (2006.01) C07C 311/47 (2006.01) C07C 317/42 (2006.01) C07D 213/40 (2006.01) C07D 213/75 (2006.01) C07D 213/79 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 295/192 (2006.01) C07D 295/205 (2006.01) C07D 295/26 (2006.01) C07D 333/20 (2006.01) C07D 333/36 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2434939

Novel antagonists of .prop.4.beta.1 integrin and/or .prop.4.beta.7 integrin of the general Formula I: wherein R1, R2, R5, L1, L2, Rb, W and Z are as defined in any one of claims 1 to 13, A represents -CH- or a nitrogen atom, and p is from 0 to 4.

L'invention concerne de nouveaux antagonistes d'.alpha.4.beta.1 intégrine et/ou d'.alpha.4.beta.7 intégrine de formule (I), où R1, R2, R5, L1, L2, Rb, W et Z sont définis dans l'une quelconque des revendications 1 à 13, A désignant -CH- ou un atome d'azote, et p étant compris entre 0 et 4.

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