Urea substituted imidazoquinoline ethers

Details Urea substituted imidazoquinoline ethers Urea substituted imidazoquinoline ethers

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2436984

Imidazoquinoline and tetrahydroimidazoquinoline compounds that contain ether and urea functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases.

La présente invention concerne des composés d'imidazoquinoléine et de tétrahydroimidazoquinoléine contenant une fonctionnalité d'éther et d'urée à la position 1, utiles en tant que modificateurs de la réponse immunitaire. Les composés et les compositions selon l'invention peuvent induire la biosynthèse de diverses cytokines et sont utiles dans le traitement d'une variété d'états comprenant les infections virales et les maladies néoplasiques.

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