C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 271/06 (2006.01) A61K 31/4245 (2006.01) A61P 7/02 (2006.01) C07C 311/47 (2006.01) C07C 317/42 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2417268
The invention relates to novel compounds of formula (I), wherein R, R1 and R2 have the meaning as cited claim 1. According to the invention, the compounds are inhibitors of the coagulation factors Xa and VIIa and can be used for treating thrombosis, myocardial infarct, arteriosclerosis, inflammation, apoplexy, angina pectoris, restenosis post-angioplasty, intermittent claudication, tumours, tumour related illnesses and/or tumour metastases.
L'invention concerne de nouveaux composés de formule (I), dans laquelle R, R?1¿ et R?2¿ ont la signification indiquée dans la revendication 1. Les composés selon l'invention sont des inhibiteurs du facteur de coagulation Xa et VIIa et peuvent être utilisés pour le traitement de thromboses, d'infarctus du myocarde, de l'artériosclérose, d'inflammations, de l'apoplexie, de l'angine de poitrine, de la resténose postangioplastie, de la claudication intermittente, de tumeurs, d'affections tumorales ou de métastases tumorales.
Barnes Christopher
Dorsch Dieter
Gleitz Johannes
Juraszyk Horst
Mederski Werner
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
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