Urinary tumor associated antigen, antigenic subunits uses...

Details Urinary tumor associated antigen, antigenic subunits uses... Urinary tumor associated antigen, antigenic subunits uses...

C - Chemistry, Metallurgy

12

P

C12P 21/08 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 14/47 (2006.01) C07K 16/30 (2006.01) C07K 16/42 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2072620

The invention provides a substantially purified antigenic polypeptide of urinary tumor associated antigen having, after reuction by beta-mercaptoethanol and separation by SDS-polyacrylamide gel electrophoresis, a molecular weight of about 90 to 100 kD. Monoclonal antibodies, methods of detecting cancers, methods of immunotherapy, methods for monitoring a malignan- cy, a method of detecting urinary tumor associated antigen, tumor cell vaccines or polypeptide vaccine and other methods relat- ing to urinary tumor associated antigen are also provided.

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