C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2642535
This invention relates to methods for determining the presence of cancer in a subject based on the analysis of the expression levels of an under-expressed tumour marker (TM) and at least one other TM. Specifically, this invention relates to the determination of a cancer, particularly bladder cancer, by performing ratio, regression or classification analysis of the expression levels of at least one under-expressed TM, particularly an under-expressed bladder TM (BTM), and at least one over-expressed TM, particularly an over-expressed BTM. In various aspects, the invention relates to kits and devices for carrying out these methods.
La présente invention concerne des méthodes pour déterminer la présence d'un cancer chez un sujet en fonction de l'analyse des niveaux d'expression d'un marqueur de tumeur (MT) sous exprimé et d'au moins un autre MT. Spécifiquement, la présente invention concerne la détection d'un cancer, en particulier d'un cancer de la vessie, en effectuant une analyse de la proportion, de la régression ou de la classe des niveaux d'expression d'au moins un MT sous exprimé, en particulier un MT de la vessie (MTV) sous exprimé, et d'au moins un MT surexprimé, en particulier un MTV surexprimé. Selon plusieurs aspects, l'invention concerne des trousses et des appareils pour appliquer lesdites méthodes.
Gowling Lafleur Henderson Llp
Pacific Edge Biotechnology Ltd.
LandOfFree
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