C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/64 (2006.01) A61K 31/4164 (2006.01) A61K 31/4166 (2006.01) A61K 31/4172 (2006.01) A61P 17/00 (2006.01) A61P 39/06 (2006.01) C07D 233/70 (2006.01)
Patent
CA 2690485
The invention relates to derivatives of urocanic acid that have improved efficacy and/or tissue penetration properties. The invention further provides use of these derivatives in a medicament for modulating an immune-related disease in an individual. Imidazole derivative, or a salt thereof, selected from O I1 W-C-R1 H- (formula 1); o I1 W-C-R1 and HN N r < 1 NH (formula 2); O O Ov ^W-C-R1 and HN N (formula 3);
La présente invention concerne des dérivés de l'acide urocanique qui ont une efficacité améliorée et/ou des propriétés améliorées de pénétration du tissu. L'invention concerne en outre l'utilisation de ces dérivés dans un médicament pour moduler une maladie du système immunitaire chez un individu. Le dérivé imidazole, ou un sel de celui-ci, est choisi parmi O Il W-C-Rl H- (formule 1); o Il W-C-Rl et HN N r < 1 NH (formule 2); O O Ov ^W-C-Rl et HN N (formule 3).
Fetherstonhaugh & Co.
Valletta Health Ip Ee B.v.
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