Urological medical devices for release of prostatically...

A - Human Necessities – 61 – L

Patent

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Details

A61L 29/16 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2687281

According to an aspect of the invention, urological medical devices are provided, which comprise a prostatically beneficial agent selected from alpha-adrenergic blockers, antispasmodic agents, anticholinergic/antimuscarinic agents, calcium channel blockers, anti-inflammatory agents, hormone-affecting agents, anti-cancer agents, and combinations thereof, among others. The urological medical devices are adapted for implantation or insertion into a subject's urinary tract, whereupon at least a portion of the prostatically beneficial agent is released into the subject's prostatic urethra. The release profile of the prostatically beneficial agent is effective to treat a prostatic disorder, for example, benign prostate hypertrophy, prostate cancer or prostatitis, among others. Other aspects of the invention are directed to treating prostatic disorders.

La présente invention concerne, selon l'un de ses aspects, des dispositifs médicaux urologiques comprenant un agent bénéfique pour la prostate sélectionné dans le groupe constitué des alphabloquants, des antispasmodiques, des anticholinergiques/antimuscariniques, des inhibiteurs calciques, des anti-inflammatoires, des agents affectant les hormones, des anti-cancéreux et des combinaisons de ceux-ci, entre autres. Les dispositifs médicaux urologiques sont conçus pour être implantés ou insérés dans les voies urinaires d'un sujet, une partie au moins de l'agent bénéfique pour la prostate étant libéré dans l'urètre prostatique du sujet. Le profil de libération de l'agent bénéfique pour la prostate est efficace pour traiter un trouble prostatique, par exemple une hypertrophie bénigne de la prostate, un cancer de la prostate ou une prostatite, entre autres. Selon d'autres aspects, la présente invention concerne le traitement des troubles prostatiques.

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