A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/205 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2512618
The combination of R-4-trimethylammonio-3-(tetra-decylcarbamoyl)-aminobutyrate and metformin is disclosed. Said combination of anti-diabetic drugs exerts a synergic action and allows the administration of the two drugs at doses such as to avoid or reduce the occurrence of side effects. The combination is also useful for improving the therapeutic cover far from mealtimes, and in postabsorption and fasting conditions.
La présente invention concerne la combinaison de R-4-triméthylammonio-3-(tétra-decylcarbamoyl)-aminobutyrate et de metformine. Cette combinaison de médicaments antidiabétiques exerce un effet de synergie et permet d'administrer ces deux médicaments à des doses qui évitent les effets secondaires ou qui les réduisent. Cette combinaison convient aussi pour améliorer la couverture thérapeutique bien au delà des heures de repas, ainsi que dans des conditions d'absorption à la suite d'un repas ou à jeun.
Giannessi Fabio
Pessotto Pompeo
Fetherstonhaugh & Co.
Sigma-Tau Industrie Farmaceutiche Riunite S.p.a.
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