A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/56 (2006.01) A61K 31/565 (2006.01) A61P 33/02 (2006.01) A61P 33/06 (2006.01) C07J 1/00 (2006.01) C07J 3/00 (2006.01)
Patent
CA 2352387
The invention provides the use of 17-ketosteroid compounds, e.g., 16.alpha.- bromoepiandrosterone, as well as derivatives, metabolites and precursors of such compounds, and pharmaceutically acceptable salts of any of these compounds, collectively defined herein as the "compounds of the present invention", to treat or prevent Toxoplasmosis or Cryptosporidiosis in patients in need of such treatment or prophylaxis. The formula (1) compounds can also be used to ameliorate or reduce one or more symptoms associated with such infections.
L'invention concerne l'utilisation de composés 17-cétostéroïdes (16.alpha.-bromo-isoandrostérone, par exemple), ainsi que des dérivés, des métabolites et des précurseurs desdits composés, et des sels pharmaceutiquement acceptables de l'un quelconque de ces composés (ci-après appelés collectivement "composés de l'invention") pour le traitement ou la prévention de la toxoplasmose ou de la cryptosporidiose chez des patients nécessitant un tel traitement ou une telle prophylaxie. Les composés de la formule (1) peuvent être également utilisés pour améliorer ou diminuer un ou plusieurs symptômes associés à de telles infections.
Ahlem Clarence Nathaniel
Frincke James Martin
Prendergast Patrick T.
Thadikonda Krupakar Paul
Hollis-Eden Pharmaceuticals Inc.
Sim & Mcburney
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