Use of 2-(3,4-dimethoxycinnamoyl)aminobenzoic acid for the...

A - Human Necessities – 61 – K

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A61K 31/195 (2006.01) A61K 31/19 (2006.01)

Patent

CA 2106172

This invention provides a pharmaceutical composition for the treatment or prevention of restenosis associated with coronary intervention, containing, as an active ingredient, 2-(3,4-dimethyoxycinnamoyl)aminobenzoic acid or a pharmaceutically acceptable salt thereof and the use of 2-(3,4-dimethoxycinnamoyl)aminobenzoic acid or a pharmaceutically acceptable salt thereof for the manufacture of a pharmaceutical for the treatment or prevention of restenosis associated with coronary intervention. A 600 mg dosage of 2-(3,4-dimethoxy- cinnamoyl)aminobenzoic acid for a treatment period of three consecutive months after coronary intervention lowers the incidence of restenosis, and reduces the degree of stenosis in patients.

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