A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/185 (2006.01) A61K 9/28 (2006.01) A61P 3/10 (2006.01) A61P 7/00 (2006.01) A61P 9/00 (2006.01) A61P 13/12 (2006.01) A61P 15/10 (2006.01) A61P 27/02 (2006.01)
Patent
CA 2507750
The present invention relates to the use of 2,5-dihydroxybenzenesulfonic compounds for the manufacture of a medicament for the regulation of nitric oxide (NO) synthesis and/or the regulation of EDHF (Endothelium-Derived- Hyperpolarizing-Factor) in the endothelium of diabetic patients, whereby the medicament is administered in a daily dose of the 2,5-dihydroxybenzenesulfonic compounds of formula (I) of < 500 mg.
L'invention concerne l'utilisation de composés 2,5-dihydroxybenzènesulfoniques pour fabriquer un médicament permettant de réguler la synthèse d'oxyde nitrique (NO) et/ou de réguler le facteur hyperpolarisant dérivé de l'endothélium (EDHF) dans l'endothélium chez des patients diabétiques. Une dose quotidienne inférieure à 500 mg de médicament comprenant des composés 2,5-dihydroxybenzènesulfoniques de formule (I) est administrée au patient.
Angulo-Frutos Javier
Esteve-Soler Jose
Saenz de Tejada-Gorman Inigo
Borden Ladner Gervais Llp
Laboratorios Del Dr. Esteve S.a.
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