Use of 2-amino-4-pyridylmethyl-thiazoline derivatives as...

Details Use of 2-amino-4-pyridylmethyl-thiazoline derivatives as... Use of 2-amino-4-pyridylmethyl-thiazoline derivatives as...

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01) A61K 31/4439 (2006.01) A61P 25/16 (2006.01) C07D 213/40 (2006.01) C07D 213/55 (2006.01) C07D 213/64 (2006.01) C07D 213/89 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2465877

The invention concerns the use of 2-amino-4-pyridylmethyl-thiazoline derivatives of formula (I), wherein: either R1 = R2 = Cl, or C1-C4 alkyl, or hydroxy; or C1-C4 alkoxy or at least one of the two R1 and R2 is hydrogen and the other a C1-C4 alkyl radical, a hydroxy, a C1-C4 alkoxy or a chlorine or their pharmaceutically acceptable salts as inhibitors of inducible NO-synthase.

La présente invention concerne l'utilisation de dérivés 2-amino-4- pyridylméthyl thiazoline de formule (I) dans laquelle soit R1 = R2 = Cl, ou alkyle(C1-C4), ou hydroxy ; ou alcoxy (C1-C4)soit au moins un des deux R1, R2 est hydrogène et l'autre est un radical alkyle (C1-C4), un hydroxy, un alcoxy (C1-C4) ou un chlore ou leurs sels pharmaceutiquement acceptables comme inhibiteurs de NO-synthase inductible.

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