Use of 2-iminothiazolidin-4-one derivatives as novel...

Details Use of 2-iminothiazolidin-4-one derivatives as novel... Use of 2-iminothiazolidin-4-one derivatives as novel...

A - Human Necessities

61

K

A61K 31/425 (2006.01)

Patent

CA 2065798

4-18612/A Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients Abstract Compounds of the formula I Image (I), in which R1 is lower alk-2-en-1-yl, lower alk-3-en-2-yl, lower alk-2-yn-1-yl or lower alkyl substituted in the 2,3-position by radicals which can be eliminated to give a double bond, R2 is hydrogen and R3 is methyl which is unsubstituted or substituted by radicals which can be eliminated together with hydrogen R2 to give a double bond or R2 and R3 are both hydrogen or lower alkyl or are together methylene and R4 is a group of the formula Ia, Ib or Ic Image in which R5 is hydrogen, lower alkyl, lower alk-2-en-1-yl or lower alk-2-yn-1-yl and R6 is a group of the formula Id or Ie Image (Id) (Ie) in which R1, R2, R3 and R5 are as defined, and their pharmaceutically acceptable salts can be used in a novel manner for the treatment of diseases of the rheumatoid type.

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