Use of 3-(1h-imidazol-4-ylmethyl)-indan-5-ol in the...

A - Human Necessities – 61 – K

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Details

A61K 31/4174 (2006.01) A61P 25/04 (2006.01)

Patent

CA 2345521

The present invention relates to a method for obtaining analgesia by administering 3-(1H-imidazol-4-ylmethyl)-indan-5-ol, its enetiomer or pharmaceutically acceptable ester or salt thereof to a mammal intraspinally. 3-(1H-imidazol-4-ylmethyl)-indan-5-ol, its enantiomer or a pharmaceutically acceptable ester or salt thereof can be administered intraspinally to a mammal obtaining analgesia without side-effects, such as sedation. The present invention also relates to a method for using the drug as an adjunct to anaesthesia by administering it intraspinally.

La présente invention concerne l'administration par voie sous-arachnoïdienne à un mammifère, en vue d'une analgésie, de 3-(1H-imidazol-4-ylméthyl)-indan-5-ol, de son énantiomère, ou de l'un de ses esters ou sels pharmaceutiquement admis. L'administration à un mammifère de 3-(1H-imidazol-4-ylméthyl)-indan-5-ol, de son énantiomère, ou de l'un de ses esters ou sels pharmaceutiquement admis, par voie sous-arachnoïdienne, permet d'aboutir à une analgésie sans effets secondaires tels que la sédation. L'invention concerne également des modalités d'utilisation de ce médicament en complément à une anesthésie pour une administration par voie sous-arachnoïdienne.

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