Use of 3,7-diazabicyclo[3,3,1]nonane compounds for the...

A - Human Necessities – 61 – K

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A61K 31/439 (2006.01) A61K 31/495 (2006.01) A61K 31/4995 (2006.01) A61P 9/06 (2006.01)

Patent

CA 2533492

The present invention relates to the use of 3,7-diazabicyclo[3,3,1]nonane compounds, preferably of 9,9-alkylene-3,7~diazabicyclo[3,3,1]nonane compounds, and most preferably to the use of tedisamil, and the physiologically acceptable acid addition salts and/or solvates thereof, for the treatment and/or prophylaxis of anti-arrhythmic events in male human patients, preferably in conversion of recent onset of atrial fibrillation (Afib) or flutter to normal sinus rhythm (NSR) in male human patients.

La présente invention concerne l'utilisation de composés de 3,7-diazabicyclo[3,3,1]nonane, de préférence des composés de 9,9-alkylène-3,7-diazabicyclo[3,3,1]nonane, et, encore mieux, l'utilisation de tedisamil, ainsi que les sels d'addition acide et/ou les solvates de ceux-ci, acceptables d'un point de vue physiologique, pour traiter et/ou prévenir des événements anti-arythmiques chez des patients humains mâles, de préférence pour faire passer un événement de fibrillation auriculaire (Afib) ou de flutter qui vient d'apparaître à un rythme sinusal normal (NSR) chez des patients humains mâles.

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