C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 261/10 (2006.01) A61K 31/42 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01) C07D 261/14 (2006.01) C07D 413/04 (2006.01) C07D 417/02 (2006.01)
Patent
CA 2092885
Use of 3-amino-substituted isoxazole derivatives for combating endoparasites, new 3-amino-substituted isoxazole derivatives, and processes for their preparation Abstract The present invention relates to the use of 3-amino- substituted isoxazole derivatives of the general formula (I) Image (I) in which R1 represents aryl or hetaryl radicals, each of which is optionally substituted by halogen, cyano, nitro, amino, aminoacyl, alkylamino, alkyl, aralkyl, halogenoalkyl, alkoxy, halogenoalkoxy, aryloxy, arylthio, halogenoalkylthio, alkyl- sulphinyl, halogenoalkylsulphinyl, alkylsulphonyl or halogenoalkylsulphonyl, R2 represents hydrogen, halogen, alkyl, halogenoalkyl, cyano, carbonylalkoxy or aryl, each Le A 28 882 of which is optionally substituted, R3 represents substituted C1-C6-alkyl, C2-C4-alkenyl and optionally substituted cycloalkylalkyl, cycloalkyl, aralkyl or aryl, substituents which may be mentioned being halogen, nitro, alkyl, halogenoalkyl, amino, alkylamino, aminoacyl, alkoxy, halogenoalkoxy, alkylthio, halogenoalkylthio, alkylsulphinyl, halosenoalkyl- sulphinyl, alkylsulphonyl, halogenoalkylsulphonyl, aryl, aryloxy or arylthio, R4 represents hydrogen or alkyl, or R3 and R4 together with the adjacent N atom represent a carbocyclic 5-, 6- ox 7-membered ring which can optionally also be interrupted by O, S or N and which is optionally substituted by C1-C4-alkyl, for combating endoparasites in medicine and veterinary medicine, to new 3-amino-substituted isoxazoles, and to their preparation. Le A 28 882
Harder Achim
Jeschke Peter
Lindner Werner
Mencke Norbert
Aktiengesellschaft Bayer
Fetherstonhaugh & Co.
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