A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/195 (2006.01)
Patent
CA 2073873
The present invention provides a method for treating or preventing certain metabolic disorders comprising the administra- tion of 3-guanidinopropionic acid (3-GPA). These metabolic disorders of human and animal metabolism, e.g hyperglycemia, im- paired glucose tolerance, hyperinsulinemia and insulin insensitivity, hyperamylinemia, excess adiposity, and hyperlipidemia, may occur in the following disease states: non-insulin dependent diabetes mellitus (NIDDM), obesity, hypertension and atherosclero- sis. 3-GPA may be administered admixed in the diet of farm animals or as a pharmaceutical preparation such as an oral tablet or capsule, by injection, or by implantable sustaind release devices thereby increasing the protein content of the carcass while de- creasing its fat content. This would produce muscle tissue with less fat.
Macrae & Co.
Pharmacia & Upjohn Company
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