A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/445 (2006.01) A61K 31/44 (2006.01)
Patent
CA 2063941
IN THE CANADIAN PATENT & TRADEMARK OFFICE PATENT APPLICATION entitled: Use of 4-amino-1-(2-pyridyl)piperidines for the preparation of a medicament for the treatment and prophylaxis of conditions deriving from disorders of the serotoninergic systems mediated by 5-HT3 receptors. in the names of: Gérard LE FUR Alberto BLANCHETTI Antonina GIUDICE Tiziano CROCI Philippe SOUBRIE Assignee: ELF SANOFI ABSTRACT OF THE DISCLOSURE The present invention concerns the use of 4-amino-1-(2-pyridyl)piperidines of general formula (I') Image (I') wherein R' represents hydrogen, a halogen atom, a methyl, methylthio, trifluoro-methyl, trifluoromethylthio, (C1-C3)alkoxy, trifluoromethoxy, 2,2,2-trifluoro- ethoxy, or phenoxy group optionally substituted with a halogen atom, a trifluoro- methyl, (C1-C3)alkyl, (C1-C3)alkoxy, (C1-C3)alkylthio, or cyano group, or of a pharmaceutically acceptable salt thereof, for the preparation of a medicament for the treatment or prophylaxis of those conditions deriving from disorders of the serotoninergic systems wherein a serotoninergic action selectively mediated by the 5-HT3 receptors is required, e.g. affective disorders, anxiety, psychotic troubles, constipation.
Bianchetti Alberto
Croci Tiziano
Giudice Antonina
Le Fur Gerard
Soubrie Philippe
Elf Sanofi
Sim & Mcburney
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