A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/352 (2006.01) A61K 31/473 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01)
Patent
CA 2669138
The invention relates to the areas of therapeutics, pharmaceuticals, drug discovery, and immunotherapy. More specifically, the present invention relates to methods of stimulating the immune system through the administration of flavone acetic acid [FAA] analogues, and in particular, the flavone acetic acid analogue, 5,6-dimethylxanthenone- 4-acetic acid (DMXAA) so as to comprise an antimicrobial therapeutic agent for the treatment of viral, fungal, bacterial or parasitic infections in humans and non-human animals. The invention is especially suitable for use in a process of treating and preventing infection by viruses (for example, rhinoviruses, enteroviruses, and influenza viruses, etc.) and bacteria (especially intracellular bacterial pathogens such as Francisella tularensis).
La présente invention concerne les domaines thérapeutiques, pharmaceutiques, ainsi que ceux de la découverte de médicaments et de l'immunothérapie. L'invention porte plus spécifiquement sur les procédés de stimulation du système immunitaire par l'administration d'analogues d'acide flavone acétique [FAA] et, en particulier, l'analogue d'acide flavone acétique, l'acide 5,6-diméthylxanthénone- 4-acétique (DMXAA) afin d'obtenir un agent thérapeutique antimicrobien pour le traitement d'infections virales, fongiques, bactériennes ou parasitaires chez les animaux humains et non humains. L'invention est tout particulièrement adaptée au traitement et à la prévention des infections virales (par exemple, les rhinovirus, les entérovirus et les virus de la grippe, etc.) et bactériennes (notamment les pathogènes bactériens intracellulaires tels que la Francisella tularensis).
Cole Leah E.
Roberts Zachary J.
Vogel Stefanie N.
Cole Leah E.
Osler Hoskin & Harcourt Llp
Roberts Zachary J.
University Of Maryland Baltimore
Vogel Stefanie N.
LandOfFree
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