Use of 5-alkylpyridazine derivatives as drugs active on the...

C - Chemistry – Metallurgy – 07 – D

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C07D 237/20 (2006.01) A61K 31/50 (2006.01) A61K 31/535 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2009502

IN THE UNITED STATES PATENT AND TRADEMARK OFFICE PATENT APPLICATION entitled: Use of 5-alkylpyridazine derivatives as drugs active on the cholinergic system in the names of: Robert BOIGEGRAIN Camille Georges WERMUTH Paul WORMS Assignee: SANOFI ABSTRACT OF THE DISCLOSURE The invention relates to the use of 5-alkyl pyridazine derivatives of the formula Image (II) in which R1 is a C1-C4 alkyl group or a phenyl group and R2 and R3 independently are a C1-C4 alkyl group, or R2 and R3, taken with the nitrogen atom to which they are bonded, from a mor- pholino group, or one of their pharmaceutically accep- table salts, for the prepartation of pharmaceutical compo- sitions for combating pathological conditions associated with a cortical cholinergic deficiency, especially for the treatment of degenerative syndromes associated with senescence.

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