A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/519 (2006.01) A61K 31/505 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2359357
The invention relates to the use of binding partners for 5-HT5-receptors in the treatment of neuropathological and in particular neurodegenerative and/or neuropsychiatric disturbances which can occur notably in cases of cerebral ischaemia, cerebral stroke, epilepsy and attacks in general, chronic schizophrenia, other psychotic illnesses, dementia, notably Alzheimer's disease, demyelination diseases, notably multiple sclerosis, and brain tumors. The invention also relates to methods, especially screening methods, for identifying and characterizing such binding partners.
L'invention concerne l'utilisation de partenaires de liaison pour les récepteurs 5-HT5 pour le traitement de troubles neuropathologiques, en particulier neurodégénératifs et/ou neuropsychiatriques qui peuvent apparaître en particulier dans le cas de l'ischémie cérébrale, de l'apoplexie cérébrale, de l'épilepsie et d'attaques en général, de la schizophrénie chronique, d'autres troubles psychotiques, de la démence, notamment de la maladie d'Alzheimer, de maladies démyélinisantes, notamment de la sclérose en plaques, et de tumeurs du cerveau. L'invention concerne également des procédés pour identifier et caractériser de tels partenaires de liaison, notamment des procédés de criblage.
Garcia-Ladona Francisco Javier
Hofmann Hans-Peter
Steiner Gerd
Szabo Laszlo
Abbott Gmbh & Co. Kg
Basf Aktiengesellschaft
Robic
LandOfFree
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