C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/437 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 231/00 (2006.01)
Patent
CA 2407445
The present invention describes compounds of formula (I): and pharmaceutically acceptable salts thereof. Compounds of formula (I) are protein kinase inhibitors and are useful in the treatment of proliferative diseases, for example, cancer, inflammation and arthritis. They may also be useful in the treatment of Alzheimer's disease and cardiovascular disease.
La présente invention concerne des composés de la formule (1) et des sels pharmaceutiquement acceptables de ces derniers. Les composés de l'invention sont des inhibiteurs de la protéine kinase et ils sont utilisés dans le traitement de maladies prolifératives telles que le cancer, les maladies inflammatoires et l'arthrite. Les composés précités peuvent également être utilisés dans le traitement de la maladie d'Alzheimer et de maladies cardiovasculaires.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
LandOfFree
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