Use of a 7.alpha.-methyl-17.alpha.-ethynyl-estrane...

Details Use of a 7.alpha.-methyl-17.alpha.-ethynyl-estrane... Use of a 7.alpha.-methyl-17.alpha.-ethynyl-estrane...

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 31/567 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) C07J 1/00 (2006.01)

Patent

CA 2283418

The invention relates to the use of a 7.alpha.-methyl-17.alpha.-ethynyl- estrane derivative having general formula (I) wherein R1 = H(OR3) or O; R2 = H or (C1-18)Acyl: R3 = H or (C1-18)Acyl; and the dotted line represents a double bond in the 4,5- or the 5,10-position for the manufacture of a medicament for the prophylaxis or the treatment of atherosclerosis.

L'invention concerne l'utilisation d'un dérivé de 7.alpha.-méthyle-17.alpha.-éthynyl-estrane présentant la formule générale (I). Dans cette dernière, R¿1? = H(OR¿3?) ou O; R¿2? = H ou Acyle (C¿1-18?); R¿3? = H ou Acyle (C¿1-18?) et les pointillés représentent une double liaison dans la position 4,5 ou 5,10 . Ce dérivé est utilisé pour la fabrication d'un médicament pour la prophylaxie ou le traitement de l'athérosclérose.

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