Use of a class of antiviral compounds to produce an agent...

Details Use of a class of antiviral compounds to produce an agent... Use of a class of antiviral compounds to produce an agent...

A - Human Necessities

61

K

A61K 31/325 (2006.01) A61K 31/40 (2006.01) A61P 31/16 (2006.01)

Patent

CA 2454167

A use of dithiocarbamate compounds of structural formula R1R2NC2H, where R1 and R2 independently = straight- or branched-chain C1-C4 alkyl, or together with the nitrogen atom form an aliphatic ring with 4 to 6 atoms, in which R1, R2 or the aliphatic ring are optionally substituted with several substituents selected from OH, NO2, NH2, COOH, SH, F, Cl, Br, I, methyl or ethyl, oxidised forms of the above compounds, in particular dimers thereof and pharmaceutically acceptable salts thereof for the production of an agent for the treatment of prevention of an infection by RNA viruses which affect the respiratory tract and cause disease is disclosed and also a disinfecting agent comprising a dithiocarbamate compound and a method for disinfection of surfaces, media and cell cultures.

L'invention concerne l'utilisation de composés de dithiocarbamate de la forme structurelle R¿1?R¿2?NC¿2?H, où R¿1? et R¿2? Représentent indépendamment l'un de l'autre un alkyle C¿1?-C¿4? Droit ou ramifié ou constituent avec l'atome d'azote un cycle aliphatique ayant 4 à 6 atomes de carbone, sachant que R¿1?, R¿2? ou le cycle aliphatique est substitué éventuellement par au moins un substituant sélectionné parmi OH, NO¿2?, NH¿2?, COOH, SH, F, Cl, Br, I, méthyle ou éthyle, et des formes oxydées de ces composés, notamment leurs dimères, ainsi que des sels pharmaceutiquement acceptables pour la production d'un produit permettant de traiter ou de prévenir une infection par virus à ARN qui affectent la zone respiratoire où ils déclenchent une maladie. L'invention concerne également un désinfectant contenant un composé de dithiocarbamate et un procédé de désinfection de surfaces, de moyens ou de cultures de cellules.

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