Use of a combination of amoxycillin and clavulanate in the...

A - Human Necessities – 61 – K

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A61K 31/43 (2006.01)

Patent

CA 2264074

Infections potentially caused by DRSP may be treated by a method which comprises administering a pharmaceutical formulation comprising either: for an adult or older child patient from 800 to 1100 mg amoxycillin and from 100 to 150 mg clavulanate in a weight ratio between 6:1 and 10:1 inclusive; or for a paediatric patient from 30 to 40 mg/kg body weight of amoxycillin and from 3 to 8 mg/kg body weight of clavulanate in a weight ratio between 6:1 and 10:1 inclusive; in combination with a pharmaceutically acceptable carrier or excipient, three times a day (tid).

Procédé permettant de traiter les infections potentiellement induites par la pneumonie à streptocoques pharmacorésistants et comportant l'administration d'une formulation pharmaceutique selon deux types de prises, trois fois par jour: pour un patient adulte ou un adolescent, de 800 à 1100 mg d'amoxycilline et de 100 a 150 mg de clavulanate dans une proportion en poids comprise entre 6:1 et 10:1 ; ou, pour un enfant en bas âge, entre 30 et 40 mg par kilo de poids corporel d'amoxycilline et entre 3 et 8 mg par kilo de poids corporel de clavulanate dans une proportion en poids comprise entre 6:1 et 10:1, en combinaison avec un excipient pharmacologiquement acceptable.

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