A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 6/00 (2006.01) A61K 8/19 (2006.01) A61K 8/44 (2006.01) A61Q 11/00 (2006.01)
Patent
CA 2377598
The present invention relates to compositions and methods for calcifying dental tissue, <i>e.g.</i> preventing or treating dental hypersensitivity. An oral composition of arginine bicarbonate and calcium carbonate promotes the formation of dentinal tubule plugs aided by combining calcium and phosphate in the fluid. In a specific example, an arginine bicarbonate/calcium carbonate mixture blocked dentinal tubules in a model system. In addition to treating dentinal sensitivity, the compositions and methods of the invention provide for calcifying exposed tooth pulp, calcifying the base or all of a pit or fissure in a tooth, and treating a carious lesion.
La présente invention concerne des compositions et des techniques de calcification des tissus dentaires, visant notamment à prévenir ou à traiter l'hypersensibilité dentaire. Une composition orale de bicarbonate d'arginine et de carbonate de calcium accélère la formation d'obturateurs de tubules dentinaires, lequel effet est renforcé par la combinaison du calcium et du phosphate dans le fluide. Dans un exemple spécifique, on utilise un mélange bicarbonate d'arginine/carbinate de calcium pour obturer les tubules dentinaires dans un système de modélisation. Les compositions et techniques selon l'invention permettent non seulement de traiter l'hypersensibilité dentinaire, mais également de calcifier la pulpe dentaire exposée, de calcifier la base ou la totalité d'un puits ou d'une fissure au niveau d'une dent, et de traiter une lésion carieuse.
Acevedo Ana Maria
Chatterjee Robi
Kleinberg Israel
Robic
The Research Foundation Of State University Of New York
LandOfFree
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