Use of a dialysis membrane for reducing blood free light...

A - Human Necessities – 61 – M

Patent

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A61M 1/34 (2006.01) A61M 1/16 (2006.01) A61M 1/18 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2567856

There is provided a method of reducing blood free light chain concentration in a subject, the method comprising the step of subjecting the subject's blood to haemodialysis, haemodiafiltration or haemofiltration. There is also provided the use of a dialysis membrane which is a membrane that allows passage of molecules having a molecular weight of up to 45kDa in presence of whole blood, and has a molecular weight exclusion limit in water of about 200kDa in the preparation of a haemodialysis unit for conducting haemodialysis, haemodiafiltration or haemofiltration on a subject to reduce blood free light chain concentration in the patient.

L'invention concerne une méthode visant à réduire la concentration de chaînes légères libres dans le sang d'un sujet, laquelle méthode consiste à soumettre le sang du sujet à l'hémodialyse, l'hémodiafiltration ou l'hémofiltration. L'invention a également pour objet l'utilisation d'une membrane à dialyse, qui permet le passage de molécules dont le poids moléculaires est supérieur à 45 kDa en présence du sang total et dont la limite d'exclusion du poids moléculaire dans l'eau est d'environ 200 kDa dans la préparation d'un matériel d'hémodialyse pour administrer l'hémodialyse, l'hémodiafiltration ou l'hémofiltration à un sujet afin de réduire la concentration de chaînes légères dans le sang du patient.

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