Use of a high molecular weight extracellular hemoglobin for...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/00 (2006.01)

Patent

CA 2637895

The present invent ion relates to the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing diseases by inhibition of calcium. Advantageously, the extracellular hemoglobin is obtained from Annelids. In particular, the invention concerns the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing cardiovascular diseases, such as hypertension, angina such as angina pectoris, Raynaud's disease, arteriopathy, tachycardia, vasospasm, ischemia, myocardial infarct ion, congestive heart failure, arrhythmia or cerebrovacular accident.

La présente invention concerne l~utilisation d~hémoglobine extracellulaire de poids moléculaire élevé dans la fabrication d~un médicament destiné à traiter et/ou prévenir des maladies par inhibition du calcium. L~hémoglobine extracellulaire est obtenue de manière avantageuse à partir d~annélides. L~invention concerne en particulier l~utilisation d~hémoglobine extracellulaire de poids moléculaire élevé lors de la fabrication d~un médicament destiné à traiter et/ou prévenir des maladies cardiovasculaires telles que l~hypertension, l~angine telle que l~angine de poitrine, la maladie de Raynaud, l~artériopathie, la tachycardie, l~angiospasme, l~ischémie, l~infarctus du myocarde, l~insuffisance cardiaque congestive, l~arythmie ou les accidents cérébrovasculaires.

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