Use of a labelled ligand having specificity for the human...

A - Human Necessities – 61 – K

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Details

A61K 51/10 (2006.01) A61K 41/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01) G01N 33/554 (2006.01) G01N 33/569 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2469901

The invention relates to the use of a labeled ligand having human CD4 specificity for producing a diagnostic used in the analysis of migration and/or distribution patterns of certain cell populations that comprise CD4 carrying cells in human individuals. The invention further relates to a composition that comprises a labeled ligand that is specific for the CD4 molecule and for CD4 carrying cells or particles, and to a method for determining the extent and the progression of diseases in which human CD4 carrying cells have a clinical significance.

La présente invention concerne l'utilisation d'un ligand marqué présentant une spécificité pour la molécule CD4 humaine afin d'établir un diagnostic en vue d'analyser des modèles de migration et/ou de distribution de populations cellulaires définies, qui comprennent des cellules portant CD4, chez des êtres humains. La présente invention concerne également une composition qui comprend un ligand marqué présentant une spécificité pour la molécule CD4 et des cellules ou particules portant CD4, ainsi qu'un procédé pour déterminer le degré et la progression de maladies pour lesquelles les cellules humaines portant CD4 sont importantes d'un point de vue clinique.

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