A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/661 (2006.01) A61K 31/726 (2006.01) A61K 31/728 (2006.01) A61K 38/17 (2006.01) A61P 19/02 (2006.01)
Patent
CA 2558497
A mixture of one or several substances from group A) lubricin, proteoglycan 4 (PRG4) and phospholipid (SAPL); with one or several substances from group B) hyaluronic acid, glycosaminoglycan and derivatives of said substances; dissolved in a solvent, used for the production of an agent for treating defective or degenerated cartelage in vivo. Said mixture can also be used to produce natural cartilage replacement in vitro.
L'invention concerne un mélange comprenant une ou plusieurs substances du groupe A) qui rassemble lubricine, protéoglycane 4 (PRG4) et phospholipide (SAPL), et une ou plusieurs substances du groupe B) qui rassemble acide hyaluronique, glycosaminoglycane et des dérivés de ces substances, en dissolution dans un solvant, et servant à produire un agent pour traiter un cartilage défectueux ou dégénéré in vivo. Le mélange selon l'invention peut également être utilisé pour produire un substitut de cartilage naturel in vitro.
Alini Mauro
Kaup Thomas
Wimmer Markus
Osler Hoskin & Harcourt Llp
Synthes (u.s.a.)
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