Use of a nk-1 receptor antagonist and an antidepressant...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/675 (2006.01) A61K 31/135 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) A61K 31/5377 (2006.01) A61K 45/06 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2266773

The present invention relates to the treatment or prevention of depression and/or anxiety by the administration of a combination of a specific class of NK-1 receptor antagonists and an antidepressant or anti-anxiety agent. The present invention also provides preclinical screens for anxiolytic and antidepressant activity of NK-1 receptor antagonists.

Traitement et prévention de la dépression et des états d'anxiété par l'administration d'une combinaison d'une classe spécifique d'antagonistes du récepteur NK-1, et d'un antidépresseur ou d'un agent anxiolytique. L'invention porte également sur des cribles précliniques pour l'activité anxiolytique et antidépressive des antagonistes du récepteur NK-1.

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