Use of a pak inhibitor for the treatment of a joint disease

A - Human Necessities – 61 – K

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A61K 38/00 (2006.01) A61P 19/02 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2532742

The invention refers to the use of a p21 -activated kinase (PAK) inhibitor for the treatment of a joint disease such as osteoarthritis or rheumatoid arthritis or for the treatment of a joint pain and the use of PAK as a target protein for the discovery of a PAK inhibitor as a medicament for the treatment of a joint disease.

L'invention concerne l'utilisation d'un inhibiteur de la kinase activée par p21 (PAK) pour le traitement d'une maladie des articulations telle que l'arthrose ou la polyarthrite rhumatoïde, ou pour le traitement d'une douleur articulaire. Elle concerne également l'utilisation de la PAK comme protéine cible en vue de découvrir un inhibiteur de la PAK en tant que médicament pour le traitement d'une maladie des articulations.

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