A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/12 (2006.01) A61K 48/00 (2006.01) A61P 31/20 (2006.01) A61P 37/04 (2006.01)
Patent
CA 2635430
The present invention relates to the use of an immunogenic composition that comprises a porcine circovirus type 2 (PCV2) antigen for treatment of several clinical manifestations (diseases). Preferably, the clinical manifestations are associated with a PCV2 infection. Preferably, they include lymphadenopathy, lymphoid depletion and/or multinucleated/giant histiocytes. Moreover, the clinical symptoms include lymphadenopalhy in combination with one or a multiple of the following symptoms in pigs: (1) interstitial pneumonia with interlobular edema, (2) cutaneous pallor or icterus, (3) mottled atrophic livers, (4) gastric ulcers, (51 nephritis and (6) reproductive disorders, e.g. abortion, stillbirths. mummies, etc. Furthermore the clinical symptoms include Pia like lesions, normally known to be associated with Lawsonia intracellularis infections.
L'invention concerne une composition immunogène contenant un antigène de circovirus porcin de type 2 (PCV2), destinée au traitement de manifestations cliniques sévères (maladies). Les manifestations cliniques sont de préférence associées à une infection par PCV2 et comportent de préférence la lymphadénopathie, la déplétion lymphoïde et/ou les histiocytes polynucléés/géants. Par ailleurs, les symptômes cliniques comportent la lymphadénopathie en combinaison avec un ou plusieurs des symptômes suivants chez le porc: (1) pneumonie interstitielle avec oedème interlobulaire; (2) pâleur cutanée ou ictère; (3) foie atrophique tacheté; (4) ulcères gastriques; (5) néphrite; et (6) troubles de la reproduction, par ex. avortements, accouchements de mort-né, foetus momifiés etc. Les symptômes cliniques comportent également des lésions de type Pia normalement associées à des infections par Lawsonia intracellularis.
Eichmeyer Marc
Hayes Phillip
Nitzel Greg
Roof Michael
Schaeffer Merrill
Boehringer Ingelheim Vetmedica Inc.
Fetherstonhaugh & Co.
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