Use of a peptide as a therapeutic agent

Details Use of a peptide as a therapeutic agent Use of a peptide as a therapeutic agent

A - Human Necessities

61

K

A61K 38/31 (2006.01) A61K 38/08 (2006.01)

Patent

CA 2698789

The present invention is directed to the use of the peptide compound D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.

L'invention concerne l'utilisation d'un composé peptidique Pyr-His-Trp-Ser- Tyr-D-Trp-Leu-Arg-Pro-NHEt comme agent thérapeutique pour la prophylaxie et/ou le traitement du cancer, de maladies auto-immunes, de maladies fibreuses, de maladies inflammatoires, de maladies neurodégénératives, de maladies infectieuses, de maladies pulmonaires, de maladies cardiaques et vasculaires et de maladies métaboliques. L'invention concerne également des compositions pharmaceutiques, de préférence sous forme de lyophilisat ou de solution tampon liquide ou de formulation de lait maternel artificiel ou de substitut du lait maternel contenant le peptide Ala-lle-Phe-lle- Pyr-His-Trp-Ser- Tyr-D-Trp-Leu-Arg-Pro-NHEt éventuellement avec au moins un véhicule, un cryoprotecteur, un lyoprotecteur, un excipient et/ou un diluant pharmaceutiquement acceptable.

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