Use of a prostaglandin in combination with an adrenergic...

A - Human Necessities – 61 – K

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A61K 31/557 (2006.01)

Patent

CA 1314220

USE OF A PROSTAGLANDIN IN COMBINATION WITH AN ADRENERGIC BLOCKING AGENT FOR REDUCTION OF INTRAOCULAR PRESSURE Abstract of The Disclosure This invention provides a method for treating ocular hypertension or glaucoma in a subject's eye. The meth- od comprises contacting the surface of the eye with an effective intraocular pressure reducing amount of a mixture of an adrenergic blocking agent and a prostaglandin or prostaglandin derivative in an ophthalmically compatible carrier, so as to reduce the intraocular pressure of the eye and maintain such re- duced intraocular pressure. This invention also provides a composition for topical treatment of ocular hypertension or glaucoma in the eye of a subject. The composition comprises an effective intraocular pressure reducing amount of a mixture of an adrenergic blocking agent and a prostaglandin or prostaglandin derivative in an ophthalmically compati- ble carrier.

562902

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