Use of a pyrazole derivative for preparing medicaments for...

A - Human Necessities – 61 – K

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A61K 31/454 (2006.01) A61K 31/366 (2006.01) A61K 31/4178 (2006.01) A61K 31/5415 (2006.01) A61K 45/06 (2006.01) A61P 1/16 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2543582

The invention relates to the use of an antagonistic compound of cannabinoid receptors CB1, said compound being derived from pyrazole and used alone or associated with another active ingredient, for preparing medicaments for the prevention and treatment of dyslipidemia and illnesses associated with dyslipidemia and/or obesity, such as the metabolic syndrome, cardiovascular risks and hepatic diseases.

Utilisation d~un composé antagoniste des récepteurs CB1 aux cannabinoïdes, dérivé du pyrazole, choisi parmi le rimonabant et le N-pipéridino-5-(4- bromophényl) -1- (2,4-dichlorophényl) -4-ethylpyrazole-3-carboxamide,seul ou associé à un autre principe actif, pour la préparation de médicaments utiles dans la prevention et le traitement des dyslipidémies et des maladies associées aux dyslipidémies et/ou à l~obésité telles que le syndrome métabolique, les risques cardiovasculaires et les maladies hépatiques.

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