Use of a silica or silica derivative as a sorption material

Details Use of a silica or silica derivative as a sorption material Use of a silica or silica derivative as a sorption material

A - Human Necessities

61

K

A61K 9/18 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01)

Patent

CA 2516096

Use of a silica or silica derivative such as, e.g., Aeroperl® as a sorption material for oils or oily-like materials. The silica or silica derivates has the ability to be loaded with a relative high amount of the oil or oily-like material and this ability is especially useful concerning formulation of pharmaceutical compositions comprising a drug substance suffering from e.g. bioavailability and/or water-solubility problems. Furthermore, the silica or silica derivative has the ability to release the oil or oily-like material when contacted with an aqueous medium and/or it has suitable tabletting properties.

L'invention concerne l'utilisation de silice ou d'un dérivé de silice tel, par exemple, Aeroperl® en tant que matériau de sorption pour les huiles ou les matières huileuses. La silice ou le dérivé de silice peut être chargée d'une quantité relativement élevée d'huile ou de matière huileuse et cette capacité est notamment utile pour la formulation de compositions pharmaceutiques comprenant une substance médicamenteuse présentant des problèmes de biodisponibilité et/ou d'hydrosolubilité par exemple. De plus, la silice ou le dérivé de silice peut libérer l'huile ou la matière huileuse lorsqu'elle/il est mis(e) en contact avec un milieu aqueux et/ou présente des propriétés de comprimé convenables.

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